Members of the Institute of Biological Chemistry, Biophysics and Bioengineering publish in high impact peer-reviewed journals collaborating widely with a range of international researchers across disciplines and participate enthusiastically in public engagement activities.

Details of our current publications by our staff are available on the HW research portal.

Highlights

Nature Transations Channels Chemistry and Biology

Selected Recent Publications

2018

A comparison of methods to assess cell mechanical properties, Pei Hsun Wu, Dikla Raz Ben Aroush, Atef Asnacios, Wei Chiang Chen, Maxim E. Dokukin, Bryant L. Doss, Pauline Durand-Smet, Andrew Ekpenyong, Jochen Guck, Nataliia V. Guz, Paul A. Janmey, Jerry S.H. Lee, Nicole M. Moore, Albrecht Ott, Yeh Chuin Poh, Robert Ros, Mathias Sander, Igor Sokolov, Jack R. Staunton, Ning Wang, Graeme Whyte, Denis Wirtz, Nature Methods Link

A catch-and-release approach to selective modification of accessible tyrosine residues, Allan, C., Kosar, M., Burr, C. V., Mackay, C. L., Duncan, R. R. & Hulme, A. N., ChemBioChem Link

Assessing progress in protecting non-smokers from secondhand smoke, Semple, S., Mueller, W., Leyland, A. H., Gray, L. & Cherrie, J. W., Tobacco Control Link

Nonanimal Approaches to Assessing the Toxicity of Inhaled Substances: Current Progress and Future Promise: Roundtable Discussion, Clippinger, A. J., Allen, D., Behrsing, H., Hinderliter, P. M., Landsiedel, R., Reinke, E. N. & Stone, V., Applied In Vitro Toxicology Link

Impact of poloxamer 188 (Pluronic F-68) additive on cell mechanical properties, quantification by real-time deformability cytometry, Guzniczak, E., Jimenez, M., Irwin, M., Otto, O., Willoughby, N. & Bridle, H., Biomicrofluidics Link

A cross-species and model comparison of the acute toxicity of nanoparticles used in the pigment and ink industries, Brown, D. M., Johnston, H. J., Gaiser, B. K., Pinna, N., Caputo, G., Culha, M., Kelestemur, S., Altunbek, M., Stone, V., Roy, J. C., Kinross, J. H. & Fernandes, T. F., Nano Impact Link

Adoption of in vitro systems and zebrafish embryos as alternative models for reducing rodent use in assessments of immunological and oxidative stress responses to nanomaterials, Johnston, H. J., Verdon, R., Gillies, S., Brown, D. M., Fernandes, T. F., Henry, T. B., Rossi, A. G., Tran, L., Tucker, C., Tyler, C. R. & Stone, V., Critical Reviews in Toxicology Link

A Flow Cytometry-based Method for the Screening of Nanomaterial-induced Reactive Oxygen Species Production in Leukocytes Subpopulations in Whole Blood, Kermanizadeh, A., Jantzen, K., Brown, D. M., Møller, P. & Loft, S, Basic and Clinical Pharmacology and Toxicology Link

A randomised control crossover trial of a theory based intervention to improve sun-safe and healthy behaviours in construction workers: study protocol, Nioi, A., Wendelboe-Nelson, C., Cowan, S., Cowie, H., Rashid, S., Ritchie, P., Cherrie, M., Lansdown, T. C. & Cherrie, J. W., BMC Public Health Link

Bio-resin for high resolution lithography-based biofabrication of complex cell-laden constructs, im, K. S., Levato, R., Costa, P. F., Castilho, M. D., Alcala-Orozco, C., van Dorenmalen, K. M. A., Melchels, F., Gawlitta, D., Hooper, G. J., Malda, J. & Woodfield, T. B. F., Biofabrication Link

Comparing Hydrogels for Human Nucleus Pulposus Regeneration: Role of Osmolarity During Expansion, Krouwels, A., Melchels, F. P. W., van Rijen, M. H. P., Öner, F. C., Dhert, W. J. A., Tryfonidou, M. A. & Creemers, L. B., Tissue Engineering Part C: Methods Link

Cylindrical microlensing for enhanced collection efficiency of small pixel SPAD arrays in single-molecule localisation microscopy, I. Gyongy, A. Davies, B. Gallinet, N.A.W. Dutton, R.R. Duncan, C. Rickman, R.K. Henderson, and P.A. Dalgarno Optics Express Link

Zinc Oxide Nanoparticles and Voltage‐Gated Human Kv11.1 Potassium Channels Interact through a Novel Mechanism, S. Piscopo E. R. Brown, Small Link

A simple and robust real-time qPCR method for the detection of PIK3CA mutations, V. Alvarez-Garcia, C. Bartos, I. Keraite, U. Trivedi, P. M. Brennan, M. Kersaudy-Kerhoas, K. Gharbi, O. Oikonomidou & N. R. Leslie, Scientific Reports Link

What should we tell shift workers to do to reduce their cancer risk?, D. M. McElvenny, J. O. Crawford, & J. W.V. Cherrie, Occupational Medicine Link

2017

Estimating past inhalation exposure to asbestos - A tool for risk attribution and disease screening, J. W. Cherrie, D. McElvenny, & K. G. Blyth, International Journal of Hygiene and Environmental Health Link

EnLightenment: High resolution smartphone microscopy as an educational and public engagement platform, L.C. Wicks, G.S. Cairns, J. Melnyk, S. Bryce, R.R. Duncan, P.A. Dalgarno, Wellcome Open Research Link

The Potential of a Novel Class of EPAC-Selective Agonists to Combat Cardiovascular Inflammation, G. Barker, E. Parnell, B. van Basten, H. Buist, D. R. Adams, S. J. Yarwood, J Cardiovasc Dev Dis Link

Optomechanical measurement of the role of lamins in whole cell deformability, T. Kolb, J. Kraxner, K. Skodzek, M. Haug, D. Crawford, K. K Maaß, K. E. Aifantis, G. Whyte, J Biophotonics Link

Prioritising action on occupational carcinogens in Europe: a socioeconomic and health impact assessment, J.W. Cherrie, S. Hutchings, M. Gorman Ng, R. Mistry, C. Corden, J. Lamb, et al, British Journal of Cancer Link

Identification of a Novel, Small Molecule Partial Agonist for the Cyclic AMP Sensor, EPAC1, E. Parnell, S. P. McElroy, J. Wiejak, G. L. Baillie, A. Porter, D.R. Adams, H. Rehmann , B. O. Smith, S. J. Yarwood, Scientific Reports Link

A robust iterative algorithm for image restoration, Y. Liu, W. Lu, EURASIP Journal on Image and Video Processing Link

2016

Monitoring Early‐Stage Nanoparticle Assembly in Microdroplets by Optical Spectroscopy and SERS, A. R. Salmon, R. Esteban, W. W. Taylor, J. T. Hugall, C. A. Smith, G. Whyte, O. A. Scherman, J. Aizpurua, C. Abell, J. J. Baumberg, Small Link

Controlling PTEN Stability: a Dominant Role for Lysine 66, A. Gupta and N. R. Leslie, J. Biol. Chem. Link

Translation Microscopy (TRAM) for super-resolution imaging, Z. Qiu, R.S. Wilson, Y. Liu, A.R. Dun, R.S. Saleeb, D. Liu, C. Rickman, M. Frame, R.R. Duncan, W. Lu, Scientific Reports Link

Gelatin-Methacryloyl Hydrogels: Towards Biofabrication-Based Tissue Repair, B. J. Klotz, D. Gawlitta, A. J. W. P. Rosenberg, J. Malda, F. Melchels, Trends in Biotechnology Link

Marker-Less Stage Drift Correction in Super-Resolution Microscopy Using the Single-Cluster PHD Filter, I. Schlangen, J. Franco, J. Houssineau, W.T.E. Pitkeathly, D. Clark I. Smal, C. Rickman, IEEE Journal of Selected Topics in Signal Processing Link

High-throughput screening of antibiotic-resistant bacteria in picodroplets, X. Liu, R. E. Painter, K. Enesa, D. Holmes, G. Whyte, C. G. Garlisi, F. J. Monsma, M. Rehak, F. F. Craig, C. A. Smith, Lab on a Chip Link

Smart-aggregation imaging for single molecule localisation with SPAD cameras, I. Gyongy, A. Davis, N.A.W. Dutton, R.R. Duncan, C. Rickman, R.K. Henderson, P.A. Dalgarno, Scientific Reports Link

Hydrogel-based reinforcement of 3D bioprinted constructs, F. Melchels, M. Blokzijl, R. Levato, Q. Peiffer, M. De Ruijter, W. E. Hennink, T. Vermonden, J. Malda, Biofabrication Link

Automated single particle detection and tracking for large microscopy datasets, R.S. Wilson, L. Yang, A. Dun, A.M. Smyth, R.R. Duncan, C. Rickman, W. Lu, Royal Society Open Research Link

Metabolic gene products have evolved to interact with the cell wall integrity pathway in Saccharomyces cerevisiae., E.A. Ugbogu, K. Wang, L.M. Schweizer, M. Schweizer, FEMS Yeast Res. Link

Further details of our publications are available on the HW research portal.