Members of the Institute of Biological Chemistry, Biophysics and Bioengineering publish in high impact peer-reviewed journals collaborating widely with a range of international researchers across disciplines and participate enthusiastically in public engagement activities.

Details of our current publications by our staff are available on the HW research portal.

Highlights

Nature Transations Channels Chemistry and Biology

Selected Recent Publications

2018

Cylindrical microlensing for enhanced collection efficiency of small pixel SPAD arrays in single-molecule localisation microscopy, I. Gyongy, A. Davies, B. Gallinet, N.A.W. Dutton, R.R. Duncan, C. Rickman, R.K. Henderson, and P.A. Dalgarno Optics Express Link

Zinc Oxide Nanoparticles and Voltage‐Gated Human Kv11.1 Potassium Channels Interact through a Novel Mechanism, S. Piscopo E. R. Brown, Small Link

A simple and robust real-time qPCR method for the detection of PIK3CA mutations, V. Alvarez-Garcia, C. Bartos, I. Keraite, U. Trivedi, P. M. Brennan, M. Kersaudy-Kerhoas, K. Gharbi, O. Oikonomidou & N. R. Leslie, Scientific Reports Link

What should we tell shift workers to do to reduce their cancer risk?, D. M. McElvenny, J. O. Crawford, & J. W.V. Cherrie, Occupational Medicine Link

2017

Estimating past inhalation exposure to asbestos - A tool for risk attribution and disease screening, J. W. Cherrie, D. McElvenny, & K. G. Blyth, International Journal of Hygiene and Environmental Health Link

EnLightenment: High resolution smartphone microscopy as an educational and public engagement platform, L.C. Wicks, G.S. Cairns, J. Melnyk, S. Bryce, R.R. Duncan, P.A. Dalgarno, Wellcome Open Research Link

The Potential of a Novel Class of EPAC-Selective Agonists to Combat Cardiovascular Inflammation, G. Barker, E. Parnell, B. van Basten, H. Buist, D. R. Adams, S. J. Yarwood, J Cardiovasc Dev Dis Link

Optomechanical measurement of the role of lamins in whole cell deformability, T. Kolb, J. Kraxner, K. Skodzek, M. Haug, D. Crawford, K. K Maaß, K. E. Aifantis, G. Whyte, J Biophotonics Link

Prioritising action on occupational carcinogens in Europe: a socioeconomic and health impact assessment, J.W. Cherrie, S. Hutchings, M. Gorman Ng, R. Mistry, C. Corden, J. Lamb, et al, British Journal of Cancer Link

Identification of a Novel, Small Molecule Partial Agonist for the Cyclic AMP Sensor, EPAC1, E. Parnell, S. P. McElroy, J. Wiejak, G. L. Baillie, A. Porter, D.R. Adams, H. Rehmann , B. O. Smith, S. J. Yarwood, Scientific Reports Link

A robust iterative algorithm for image restoration, Y. Liu, W. Lu, EURASIP Journal on Image and Video Processing Link

2016

Monitoring Early‐Stage Nanoparticle Assembly in Microdroplets by Optical Spectroscopy and SERS, A. R. Salmon, R. Esteban, W. W. Taylor, J. T. Hugall, C. A. Smith, G. Whyte, O. A. Scherman, J. Aizpurua, C. Abell, J. J. Baumberg, Small Link

Controlling PTEN Stability: a Dominant Role for Lysine 66, A. Gupta and N. R. Leslie, J. Biol. Chem. Link

Translation Microscopy (TRAM) for super-resolution imaging, Z. Qiu, R.S. Wilson, Y. Liu, A.R. Dun, R.S. Saleeb, D. Liu, C. Rickman, M. Frame, R.R. Duncan, W. Lu, Scientific Reports Link

Gelatin-Methacryloyl Hydrogels: Towards Biofabrication-Based Tissue Repair, B. J. Klotz, D. Gawlitta, A. J. W. P. Rosenberg, J. Malda, F. Melchels, Trends in Biotechnology Link

Marker-Less Stage Drift Correction in Super-Resolution Microscopy Using the Single-Cluster PHD Filter, I. Schlangen, J. Franco, J. Houssineau, W.T.E. Pitkeathly, D. Clark I. Smal, C. Rickman, IEEE Journal of Selected Topics in Signal Processing Link

High-throughput screening of antibiotic-resistant bacteria in picodroplets, X. Liu, R. E. Painter, K. Enesa, D. Holmes, G. Whyte, C. G. Garlisi, F. J. Monsma, M. Rehak, F. F. Craig, C. A. Smith, Lab on a Chip Link

Smart-aggregation imaging for single molecule localisation with SPAD cameras, I. Gyongy, A. Davis, N.A.W. Dutton, R.R. Duncan, C. Rickman, R.K. Henderson, P.A. Dalgarno, Scientific Reports Link

Hydrogel-based reinforcement of 3D bioprinted constructs, F. Melchels, M. Blokzijl, R. Levato, Q. Peiffer, M. De Ruijter, W. E. Hennink, T. Vermonden, J. Malda, Biofabrication Link

Automated single particle detection and tracking for large microscopy datasets, R.S. Wilson, L. Yang, A. Dun, A.M. Smyth, R.R. Duncan, C. Rickman, W. Lu, Royal Society Open Research Link

Metabolic gene products have evolved to interact with the cell wall integrity pathway in Saccharomyces cerevisiae., E.A. Ugbogu, K. Wang, L.M. Schweizer, M. Schweizer, FEMS Yeast Res. Link

2015

Reinforcement of hydrogels using three-dimensionally printed microfibres, J. Visser, F. P. W. Melchels, J. E. Jeon, E. M. van Bussel, L. S. Kimpton, H. M. Byrne, W. J. A. Dhert, P. D. Dalton, D. W. Hutmacher, J. Malda, Nature Communications Link

Mechanism of neutrophil activation and toxicity elicited by engineered nanomaterials, H. Johnston, D. M.Brown, N. Kanase, M. Euston, B. K. Gaiser, C. T.Robb, E. Dyrynda, A. G.Rossi, E. R. Brown and V. Stone, Toxicology in Vitro Link

Visualization of the Serratia Type VI Secretion System Reveals Unprovoked Attacks and Dynamic Assembly, A.J. Gerc, A. Diepold, K. Trunk, M. Porter, C. Rickman, J.P. Armitage, N.R. Stanley-Wall, S.J. Coulthurst, Cell Reports Link

Functionally distinct groups of inherited PTEN mutations in autism and tumour syndromes, L. Spinelli, F. M. Black, J. N. Berg, B. J. Eickholt and N.R. Leslie J. Med Genet Link

The future of EPAC-targeted therapies: agonism versus antagonism, G. Barker, E. Parnell, B. van Basten, H. Buist, D. R. Adams, S. J. Yarwood, J Cardiovasc Dev Dis Link

Further details of our publications are available on the HW research portal.