REF: EGIS2017SM

Applications are invited from candidates interested in studying towards a PhD in mathematical modelling of blood flow and cell-tissue interactions in the context of two specific clinically-relevant processes: remodelling in the heart following heart attack, and metastatic tumour spread associated with breast carcinoma. The former involves the recruitment and differentiation of tissue cells, whilst the latter is characterised by a loss of cell-cell adhesion and changes to cell-matrix adhesion. However, it is not currently known how these processes are affected by the local microenvironment and the modelling will be used to give valuable insights into the importance of mechanical/biochemical factors and blood perfusion on cell dynamics and clinical outcome. The modelling will be informed throughout by measured cell data obtained from collaborative laboratories. Dissemination of results at both national and international conferences will be strongly encouraged.

The project is part of the £2.5m EPSRC Centre for Multiscale Soft Tissue Mechanics (http://www.softmech.org) and the successful candidate will be expected to liaise regularly with academic, clinical, and industrial partners throughout the UK.

Funding Notes 
This is a full scholarship which will cover tuition fees and provide an annual stipend of £14,553 for the 42 month duration of the studentship.

Eligibility
Applicants should have obtained a first or upper second class honours degree in mathematics, physics or other numerate discipline and a strong C++ programming background is essential. The scholarship will be awarded by competitive merit, taking into account the academic ability of the applicant.  

How to Apply 
Please complete our online application form.

Please select PhD programme Life Sciences and include the full project title, reference number and supervisor on your application form. You will also need to provide a CV, a supporting statement, a copy of your degree certificate and relevant transcripts and an academic reference. 

Informal enquiries should be addressed to the project supervisor, Professor Steven McDougall: s.r.mcdougall@hw.ac.uk 

Timetable
The closing date for applications is 28th February 2018. The successful candidate will be expected to start in April 2018.