Maïwenn Kersaudy-Kerhoas

Associate Professor

Telephone
+44 (0)131 451 4171
Email
m.kersaudy-kerhoas@hw.ac.uk
Address
EM3.50
Heriot-Watt University
Research
  • Microfluidics
  • Lab-on-a-Chip
  • Blood Plasma Separation
  • Non-invasive Prenatal Testing (NIPT)
  • Microchimerism, circulating DNA
Selected publications

Alvarez Garcia, V., Bartos, C., Keraite, I., Trivedi, U., Brennan, P. M., Gharbi, K., ... Leslie, N. R. (2018). A simple and robust real-time qPCR method for the detection of PIK3CA mutations. Scientific Reports, 8, [4290]. DOI: 10.1038/s41598-018-22473-9.Link

Ongaro, A. E., Keraite, I., Liga, A., Conoscenti, G., Coles, S., Schulze, H., ... Kersaudy-Kerhoas, M. (2018). Laser Ablation of Poly(lactic acid) Sheets for the Rapid Prototyping of Sustainable, Single-Use, Disposable Medical Microcomponents. ACS Sustainable Chemistry and Engineering, 6(4), 4899–4908. DOI: 10.1021/acssuschemeng.7b04348. Link

Ashour, M., & Kersaudy-Kerhoas, M. (2017). Microfluidic snap-fit assembly enabled by additive manufacturing. In J. Gao, M. El Souri, & S. Keates (Eds.), Advances in Manufacturing Technology XXXI (Vol. 6, pp. 129-134). (Advances in Transcdisciplinary Engineering; Vol. 6). Amsterdam: IOS Press. DOI: 10.3233/978-1-61499-792-4-129 Link

Vliegenthart, A. D. B., Berends, C., Potter, C. M. J., Kersaudy-Kerhoas, M., & Dear, J. W. (2017). microRNA-122 can be measured in capillary blood which facilitates point-of-care testing for drug-induced liver injury. British Journal of Clinical Pharmacology. DOI: 10.1111/bcp.13282. Link

Bridle, H., Morton, J. A. S., Cameron, P., Desmulliez, M. P. Y., & Kersaudy-Kerhoas, M. (2016). Design of problem-based learning activities in the field of microfluidics for 12- to 13-year-old participants—Small Plumbing!: empowering the next generation of microfluidic engineers. Microfluidics and Nanofluidics, 20(7), [103]. DOI: 10.1007/s10404-016-1770-x.
Link

Liga, A., Morton, J. A. S., & Kersaudy-Kerhoas, M. (2016). Safe and cost-effective rapid-prototyping of multilayer PMMA microfluidic devices. Microfluidics and Nanofluidics, 20(12), [164]. DOI: 10.1007/s10404-016-1823-1. Link

Gandi, S. K., Watson, D., Kersaudy-Kerhoas, M., Desmulliez, M. P. Y., Bachmann, T., & Bridle, H. (2015). Impact of microfluidic processing on bacterial ribonucleic acid expression. Biomicrofluidics, 9(3), [031102]. DOI: 10.1063/1.4921819. Link

Kersaudy-Kerhoas, M., Desmulliez, M. P. Y., & Norman, J. (2014). 2.5 direct fetal DNA fraction enrichment using microfluidic sample preparation of maternal blood for non-invasive prenatal testing. Archives of Disease in Childhood, 99(Suppl 1), A2. DOI: 10.1136/archdischild-2014-306576.5. Link

Biography

 Dr Kersaudy-Kerhoas is an Royal Academy of Engineering/EPSRC Fellow in the School of Engineering and Physical Sciences at Heriot-Watt University. She holds a research MSc degree in micro and nanotechnologies from the Technical University of Lille (France), and an MSc degree from the Institut Superieur de l'Electronique et du Numerique (Brest-Lille, France). She was awarded a PhD at Heriot-Watt in July 2010 entitled "Design, fabrication and test of blood plasma separation Microsystems". These PhD studies involved the development of a microfluidic chip for blood plasma extraction for detection of cell-free nucleic acids (DNA, RNA). Responsibilities included the design and simulation of a novel plasma extraction method, as well as setting-up a microfluidic laboratory. Maïwenn was also responsible for developing a partnership with an industrial chip manufacturer, Epigem Ltd, and overseeing the production of over 200 chips to sustain intensive testing. In parallel, she developed a collaboration with the division of Pathway Medicine in the University of Edinburgh where she gained access to Class II labs and characterized biologically these chips using blood samples obtained from the blood bank in Edinburgh. Maïwenn also initiated and set-up a clinical study in collaboration with NHS Lothian, to demonstrate the concept of amplifying fetal cell-free DNA in maternal plasma extracted on-chip. More recently she has taken part in the development of the successful Genome Segments Assembly programme run by Scottish Enterprise (SE). This research work dealt with the development of disposable microfluidic chips for the assembly and purification of genome segments in the context of synthetic biology.